GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
Synonyms: 2,3,7,8-Tetrachlorodibenzo-p-dioxin | Dioxin
Compound class:
Synthetic organic
Comment: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), one of the most potent non-genotoxic tumor-promoting substances known. TCDD toxicity is primarily mediated through the aryl hydrocarbon receptor (AhR) where it acts as a high-affinity ligand.
|
|
Selectivity at other protein targets | ||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | |||||||||||||||||||||||||||||||||
|