Compound class:
Synthetic organic
Comment: PF-06684511 with high specific binding to BACE1 in brain, upon radiolabeling with [18F] demonstrated favourable uptake and high in vivo specificity in nonhuman primate, suggesting its potential for imaging BACE1 in vivo [1].
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Bioactivity Comments |
Binding of [18F]PF-06684511 to BACE1 will be similar to that of the unlabelled molecule [1]. |