BsAb (CD89-CD20)   Click here for help

GtoPdb Ligand ID: 9833

Immunopharmacology Ligand
Compound class: Antibody
Comment: BsAb (CD89-CD20) is a bi-valent antibody that binds tumour-expressed CD20 and FcαRI (CD89) on myeloid cells [1].
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Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Fc fragment of IgA receptor Primary target of this compound Hs Antibody Binding 8.5 pKd - 1
pKd 8.5 (Kd 3.25x10-9 M) [1]
Description: FACS analysis of antibody binding to CD89-positive PMN cells.
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Primary target of this compound Hs Antibody Binding 8.0 pKd - 1
pKd 8.0 (Kd 9.37x10-9 M) [1]
Description: FACS analysis of antibody binding to CD20-expressing Raji cells.