BsAb (CD89-CD20)   Click here for help

GtoPdb Ligand ID: 9833

Immunopharmacology Ligand
Compound class: Antibody
Comment: BsAb (CD89-CD20) is a bi-valent antibody that binds tumour-expressed CD20 and FcαRI (CD89) on myeloid cells [1].
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Immunopharmacology Comments
BsAb (CD89-CD20) is a bispecific mAb designed to show that recruiting CD89-expressing immune effector cells (macrophages and neutrophils) to tumour cells is an effective immuno-oncology strategy.