Ligand id: 9944

Name: MM-433593

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 73.22
Molecular weight 447.13
XLogP 5.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
In the absence of in vitro affinity data in the paper [1], a value has been extracted from patent US20150175599 where MM-433593 is Example 76 [2].
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Fatty acid amide hydrolase Hs Inhibitor Inhibition 7.0 pIC50 -
pIC50 7.0 (IC50 1x10-7 M)