Synonyms: Colobreathe® | polymyxin E | Promixin®
colistin is an approved drug (UK (2006))
Compound class:
Natural product
Comment: Colistin is a cyclic polypeptide (IUPAC condensed sequence Unk-Dab-Thr-Dab-Dab(1)-Dab-D-Leu-Leu-Dab-Dab-Thr-(1)) antibacterial from Bacillus colistinus. It contains Polymyxins E1 and E2 and acts as a detergent on cell membranes.
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For extended ADME data see the following: Electronic Medicines Compendium (eMC) |