anumigilimab   Click here for help

GtoPdb Ligand ID: 11761

Synonyms: CSL-324 | CSL324
Compound class: Antibody
Comment: Anumigilimab (CSL-324) is a clinical stage monoclonal antibody that targets colony stimulating factor 3 receptor (CSF3R). It was developed by CSL Behring for potential efficacy in inflammatory/autoimmune diseases. The heavy and light chain peptide sequences for anumigilimab are claimed in patent WO2012171057A1 [1].
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No information available.
Summary of Clinical Use Click here for help
Anumigilimab (CSL-324) is in early stage clinical development. Study NCT04519424 to determine anumigilimab's ability to reduce inflammation in patients with severe COVID-19 was withdrawn (for business reasons), before any patients were recruited.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT03972280 Safety and Pharmacokinetics of Repeat Doses of CSL324 in Subjects With Hidradenitis Suppurativa and Palmoplantar Pustulosis Phase 1 Interventional CSL Behring
NCT04570267 Pharmacokinetics and Safety of Subcutaneous CSL324 in Healthy Japanese and White Subjects Phase 1 Interventional CSL Behring