Synonyms: Gramplus® | Octofene®
clofoctol is an approved drug
Compound class:
Synthetic organic
Comment: Clofoctol is an antibacterial compound that exhibits bacteriostatic activity against Gram-positive organisms, including common respiratory tract pathogens.
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No information available. |
Summary of Clinical Use |
Clofoctol is well absorbed after oral or rectal administration and accumulates in lung tissue, which may explain its efficacy in bacterial respiratory infections [1]. It was marketed in France (under the trade name Octofene®) between 1978 and 2005. A rectal formulation (Gramplus®) is still in clinical use in Italy to treat bacterial infections of the upper respiratort tract and to prevent infection following ear, nose and throat surgery. |