Ligand id: 134

Name: methysergide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 57.5
Molecular weight 353.21
XLogP 1.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of migraine and cluster headaches. Use of this drug is discontinued in the US.
Mechanism Of Action and Pharmacodynamic Effects
Serotonin receptor antagonist acting on the central nervous system leading to smooth muscle constriction.