Ligand id: 1883

Name: PGE2

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View more information in the IUPHAR Pharmacology Education Project: prostaglandin e2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 12
Topological polar surface area 94.83
Molecular weight 352.22
XLogP 2.79
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the termination of pregnanacy and the induction of labour.
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of dinoprostone is unknown but for an overview of its actions, please see the entry on DrugBank linked to from this ligand page.