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Synonyms: Canesten® | Lotrimin®
clotrimazole is an approved drug (FDA (1975))
Compound class: Synthetic organic
Comment: Clotrimazole is an anti-fungal agent.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: clotrimazole
|No information available.
|Summary of Clinical Use
|Used for the local treatment of fungal and yeast infections of the skin such as ringworm, athlete's foot and jock itch, in additional to the treatment of vaginal yeast infections.
|Mechanism Of Action and Pharmacodynamic Effects
|The primary mechanism of action of clotrimazole is the inhibition of fungal growth via the disruption of cell walls.