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dydrogesterone is an approved drug (FDA-no information available-discontinued)
Compound class: Synthetic organic
Comment: Dydrogesterone is a synthetic progestogen with no androgenic or estrogenic properties which unusually does not inhibit ovulation.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|No information available.
|Summary of Clinical Use
|Dydrogesterone is used to treat irregular menstrual cycles and to prevent miscarriage in at-risk patients.
|Mechanism Of Action and Pharmacodynamic Effects
|Dydrogesterone acts on uterine progesterone receptors to regulate the healthy growth and menstrual shedding of the endometrium