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Synonyms: Duvoid® | Urecholine®
bethanechol is an approved drug (FDA (no history prior to 1948))
Compound class: Synthetic organic
Comment: Bethanechol is structurally and pharmacologically related to acetylcholine.
Marketed formulations may contain bethanechol chloride (PubChem CID 11548).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: bethanechol
|No information available.|
|Summary of Clinical Use|
|Bethanechol increases smooth muscle tone, and can be used following abdominal surgery to promote GI tract motility or to promote bladder function in patients with non-bostrictive urinary retention.|
|Mechanism Of Action and Pharmacodynamic Effects|
|The predominantly muscarinic actions of bethanechol directly stimulate cholinergic receptors in the parasympathetic nervous system.|