oxybutynin   Click here for help

GtoPdb Ligand ID: 359

Synonyms: Cystrin® | Ditropan® | oxybutynin chloride
Approved drug
oxybutynin is an approved drug (FDA (1975), EMA (2004))
Compound class: Synthetic organic
Comment: Oxybutynin is a racemic mixture of stereoisomers. We show the non-chiral molecule to represent the mixture. PubChem lists all 3 isomers here.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: oxybutynin

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 49.77
Molecular weight 357.23
XLogP 4.34
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CCN(CC#CCOC(=O)C(c1ccccc1)(C1CCCCC1)O)CC
Isomeric SMILES CCN(CC#CCOC(=O)C(c1ccccc1)(C1CCCCC1)O)CC
InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
No information available.
Summary of Clinical Use Click here for help
Used in the treatment of overactive bladder.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Inhibition of the muscarinic action of acetylcholine on smooth muscle detrusor activity of the bladder is decreased.
External links Click here for help