Ligand id: 4288

Name: piracetam

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 63.4
Molecular weight 142.07
XLogP -1.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Piracetam is approved in the UK for the treatment of myoclonus, in combination with other anti-myoclonic therapies. It is authorised for clinical use in other European nations, and Asian and South American countries, but is not approved by the US FDA.
Mechanism Of Action and Pharmacodynamic Effects
Piracetam is a weak positive allosteric modulator of the AMPA receptor, but this may not be its primary mechanism of action, nor convey its clinical effects.
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