cephradine   Click here for help

GtoPdb Ligand ID: 4830

Synonyms: cefradine | Infexin® | Velocef®
Approved drug
cephradine is an approved drug (FDA (1974, prior history not available ))
Compound class: Synthetic organic
Comment: Cefradine is a cephalosporin antibiotic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 138.03
Molecular weight 349.11
XLogP -2.46
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=C(C(C1=CCC=CC1)N)NC1C(=O)N2C1SCC(=C2C(=O)O)C
Isomeric SMILES O=C([C@@H](C1=CCC=CC1)N)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C
InChI InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
InChI Key RDLPVSKMFDYCOR-UEKVPHQBSA-N
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Summary of Clinical Use Click here for help
Cefradine is used to treat bacterial infections
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Cefradine inhibits bacterial cell wall synthesis resulting in bacterial cell lysis and death.