cephradine   

GtoPdb Ligand ID: 4830

Synonyms: cefradine | Infexin® | Velocef®
cephradine is an approved drug (FDA (1974, prior history not available ))
Compound class: Synthetic organic
Comment: Cefradine is a cephalosporin antibiotic
2D Structure
Click here for structure editor
Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 138.03
Molecular weight 349.11
XLogP -2.46
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES O=C(C(C1=CCC=CC1)N)NC1C(=O)N2C1SCC(=C2C(=O)O)C
Isomeric SMILES O=C([C@@H](C1=CCC=CC1)N)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C
InChI InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
InChI Key RDLPVSKMFDYCOR-UEKVPHQBSA-N
No information available.
Summary of Clinical Use
Cefradine is used to treat bacterial infections
Mechanism Of Action and Pharmacodynamic Effects
Cefradine inhibits bacterial cell wall synthesis resulting in bacterial cell lysis and death.