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Ligand id: 5463
View more information in the IUPHAR Pharmacology Education Project: etomidate
Molecular properties generated using the CDK
|No information available.|
|Summary of Clinical Use|
|Etomidate is used with other drugs to induce general anesthesia for short surgeries.|
|Mechanism Of Action and Pharmacodynamic Effects|
|Etomidate prolongs the thalamic post-synaptic inhibitory effect of GABA by binding to a distinct site associated with the Cl- ionophore at the GABAA receptor.
Due to the complex and varied nature of the precise subunit composition of GABAA receptors, and a paucity of affinity data with definitive molecular details, we have not tagged a primary target for this drug.