Synonyms: BCX 2600 | Diacomit ®
stiripentol is an approved drug (EMA (2007), FDA (2018))
Compound class:
Synthetic organic
Comment: Stiripentol is an orally active anti-epilepsy drug. Chemically is a mixture of enantiomers. The structure shown here does not specify stereochemistry at the chiral centres and is used to represent the mixture. Click here to view the PubChem records for associated stereoisomers.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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No information available. |
Summary of Clinical Use |
May be used as an adjunct in the treatment of epilepsy. In particular, this drug is indicated for the treatment of severe myoclonic epilepsy in infancy (SMEI or Dravet's syndrome). FDA approval as a treatment for the siezures associated with Dravet's syndrome was granted in August 2018, with approval including children 2 years of age and older whose symptoms are inadequately controlled by clobazam. |
External links |
For extended ADME data see the following: European Medicines Agency (EMA) |