Ligand id: 5757

Name: vestipitant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 35.58
Molecular weight 491.18
XLogP 5.54
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Vestipitant has been investigated in Phase II clinical trials as potential antiemetic [4] and anxiolytic drug [1], and as a treatment for tinnitus and insomnia [3]. Click here to link to's list of Phase II vestipitant trials, and here to access the GSK clinical study register details for this compound.