Ligand id: 5797

Name: D-phenylalanine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 63.32
Molecular weight 165.08
XLogP -1.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
D-phenylalanine is not an approved drug. It is sold as a dietary supplement with purported mood enhancing effects.
Mechanism Of Action and Pharmacodynamic Effects
D-phenylalanine has been reported to enhance endorphin levels and diminish pain, which may be due to its ability to inhibit carboxypeptidase A-induced enkephalin breakdown [1].