D-phenylalanine   

GtoPdb Ligand ID: 5797

Synonyms: D-(+)-phenylalanine
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 63.32
Molecular weight 165.08
XLogP -1.38
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES NC(C(=O)O)Cc1ccccc1
Isomeric SMILES N[C@@H](C(=O)O)Cc1ccccc1
InChI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
InChI Key COLNVLDHVKWLRT-MRVPVSSYSA-N
No information available.
Summary of Clinical Use
D-phenylalanine is not an approved drug. It is sold as a dietary supplement with purported mood enhancing effects.
Mechanism Of Action and Pharmacodynamic Effects
D-phenylalanine has been reported to enhance endorphin levels and diminish pain, which may be due to its ability to inhibit carboxypeptidase A-induced enkephalin breakdown [1].