compound 2 [PMID: 22911925]

Ligand id: 6950

Name: compound 2 [PMID: 22911925]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 133.84
Molecular weight 592.31
XLogP 5.33
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Compounds in this paper fulfill criteria for Alzheimer's Disease efficacy in animal models but none are yet declared as clinical candidates.[2]