Synonyms: Zohydro®
hydrocodone is an approved drug (FDA (no approval history prior to 2013))
Compound class:
Synthetic organic
Comment: Hydrocodone is a semi-synthetic opioid receptor agonist.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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No information available. |
Summary of Clinical Use ![]() |
Used to treat severe pain, and as a cough suppressant. In November 2014 an extended release formulation, Hysingla ER, was approved by the US FDA. Hysingla ER contains hydrocodone bitartrate (PubChem CID 20831824) and is intended for use only where alternative treatment options are ineffective, not tolerated or do not provide adequate pain management. The formulation of Hysingla ER is designed to make it very difficult to be crushed, broken up or dissolved, with the aim of severely limiting its appeal as a substance of prescription opioid abuse via nasal inhalation or injection. |