Synonyms: Navelbine®
vinorelbine is an approved drug (FDA (1994))
Compound class:
Synthetic organic
Comment: Vinorelbine is an anti-mitotic chemotherapy drug.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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No information available. |
Summary of Clinical Use |
Used to treat breast cancer, non-small cell lung cancer and rhabdomyosarcoma. This drug may be used alone or in combination with other medications. |
Mechanism Of Action and Pharmacodynamic Effects |
Vinorelbine is a semi-synthetic vinca alkaloid that inhibits tubulin [1] and interferes with normal microtubule function. This causes mitotic arrest and cell death. |
External links |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com |