carbinoxamine   Click here for help

GtoPdb Ligand ID: 7139

Synonyms: carbinoxamine maleate | Clistin®
Approved drug
carbinoxamine is an approved drug (FDA (2003))
Compound class: Synthetic organic
Comment: Carbinoxamine is an antihistamine.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 25.36
Molecular weight 290.12
XLogP 2.62
No. Lipinski's rules broken 0
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Canonical SMILES CN(CCOC(c1ccccn1)c1ccc(cc1)Cl)C
Isomeric SMILES CN(CCOC(c1ccccn1)c1ccc(cc1)Cl)C
InChI InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3
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Summary of Clinical Use Click here for help
Used to treat the symptoms of many allergic conditions, and rhinitis associated with colds.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Carbinoxamine blocks the action of endogenous histamine at the histamine H1 receptor.