Ligand id: 7150

Name: clopidogrel

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 57.78
Molecular weight 321.06
XLogP 2.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Clopidogrel is used for its anti-clotting action in patients with conditions such as acute coronary syndrome, myocardial infarction, peripheral vascular diseases and stroke.
Mechanism Of Action and Pharmacodynamic Effects
Clopidogrel prevents adenosine diphosphate (ADP) from binding to platelet membrane P2Y12 receptors (P2RY12). This receptor plays a role in platelet aggregation and thrombus formation [1], thus its inhibition reduces the risk of thrombus formation.
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