Ligand id: 7255

Name: oxprenolol

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View more information in the IUPHAR Pharmacology Education Project: oxprenolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 50.72
Molecular weight 265.17
XLogP 2.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat angina, hypertension and cardiac arrythymias. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
Oxprenolol antagonises the effects of endogenous epinephrine and norepinephrine at β1-adrenoceptors in cardiac and vascular smooth muscle cells. This decreases heart rate, cardiac output, and blood pressure. See the DrugBank link for further details.
External links