Ligand id: 7284

Name: propiomazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 48.85
Molecular weight 340.16
XLogP 4.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat the symptoms of many psychotic conditions. See the DrugBank link for further details. There is no information regarding approval for clinical use of this drug on the US FDA or European Medicines Agency websites. Individual national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
This drug’s molecular mechanism of action (MMOA) is complex, involving antagonism of receptors for several neurotransmitters. The drug's antipsychotic effect is most likely due to antagonism of dopamine and serotonin 5-HT2 receptors. Antagonism of the histamine H1 receptor likely underlies the drug's sedative action. See the DrugBank link for further details.