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Synonyms: Alamast® | Alegysal® | BMY-26517
pemirolast is an approved drug (FDA (1999))
Compound class: Synthetic organic
Comment: Pemirolast is an antihistamine.
Marketed formulations may contain pemirolast potassium salt (PubChem CID 443866).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|No information available.|
|Summary of Clinical Use|
|Pemirolast is contained in opthalmic solutions used to treat the symptoms of seasonal allergic conjunctivitis, including itching, redness and swelling.|
|Mechanism Of Action and Pharmacodynamic Effects|
|Pemirolast blocks the action of endogenous histamine at histamine H1 receptor. The drug inhibits eosinophil infiltration in the eye and prevents their release of inflammatory mediators.|
For extended ADME data see the following: