Ligand id: 7747

Name: inecalcitol

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 60.69
Molecular weight 400.3
XLogP 5.54
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Inecalcitol has been investigated as a treatment in prostate cancer [1], psoriasis and hyperparathyroidism. In 2014 both the European Medicines Agency and US FDA granted this compound orphan designation for the treatment of chronic lymphocytic leukemia / small lymphocytic lymphoma.