Ligand id: 8300

Name: aclerastide

No information available.
Summary of Clinical Use
Aclerastide is being assessed in Phase III clinical trial as a treatment for diabetic foot ulcers.
Mechanism Of Action and Pharmacodynamic Effects
In animal studies histological examination reveals that topically delivered aclerastide increases collagen deposition and neoangiogenesis at the site of wounds, which leads to re-epithelialization and full skin regeneration [2]. This action may be the result of aclerastide-induced neutrophil and macrophage recruitment at the site of application.