Synonyms: DS-5565
Compound class:
Synthetic organic
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No information available. |
Summary of Clinical Use |
Mirogabalin is being assessed in Phase 3 clinical trial for pain relief, in particular for pain associated with diabetic neuropathy, postherpetic neuralgia and fibromyalgia. |
Mechanism Of Action and Pharmacodynamic Effects |
Mirogabalin acts in a similar fashion to pregabalin, but whilst the latter interacts with both α2δ1 and α2δ2 voltage-gated calcium-channel ligand subunits, mirogabalin is selective for α2δ1 subunits, and lacks pregabalin's central nervous system (CNS) side effects. |