IFN-α2b (recombinant human)   Click here for help

GtoPdb Ligand ID: 8338

Synonyms: Intron A® | intronA
Approved drug
IFN-α2b (recombinant human) is an approved drug (FDA (1986))
Comment: The sequence of IFN-α2b, differs in only one residue from the sequence of the endogenous peptide, with Lys23 being replaced by Arg.
No information available.
Summary of Clinical Use Click here for help
IFN-α2b is used clinically to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, condylomata acuminata (anogenital warts), AIDS-related Kaposi's sarcoma, chronic hepatitis B and chronic hepatitis C.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
IFN-α2b activates interferon receptors to produce anti-viral, anti-proliferative, anti-tumor and immunomodulatory effects.