IFN-α2b (recombinant human)   Click here for help

GtoPdb Ligand ID: 8338

Synonyms: Intron A® | intronA
Approved drug
IFN-α2b (recombinant human) is an approved drug (FDA (1986))
Compound class: Peptide or derivative
Comment: The sequence of IFN-α2b, differs in only one residue from the sequence of the endogenous peptide, with Lys23 being replaced by Arg.
Peptide Sequence Click here for help
CDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETL
LDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQES
LRSKE
Chemical Modification
Disulphide bonds exist between Cys1 and Cys98, and Cys29 and Cys128.