Ligand id: 9048

Name: MK-0812

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 63.69
Molecular weight 469.26
XLogP 2.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
MK-0812 has completed a Phase II efficacy, tolerability and safety clinical trial in patients with rheumatoid arthritis (NCT00542022), and a Phase II trial in patients with relapsing-remitting multiple sclerosis (NCT00239655).