Ligand id: 9497

Name: BMS-817399

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 89.87
Molecular weight 438.23
XLogP 2.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
BMS-817399 failed to show clinical efficacy in a 12 week Phase 2 proof-of-concept trial in patients with moderate to severe RA.