Ligand id: 9818

Name: elenbecestat

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 127.79
Molecular weight 437.11
XLogP 1.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
See NCT03036280 The trial, MissionAD2, is a 24-month treatment, multicenter, double-blind, placebo-controlled, parallel group, Phase 3 study in participants with early Alzheimer's disease (EAD). It will include mild cognitive impairment (MCI) due to AD/prodromal AD and the early stages of mild AD and will be conducted to evaluate the efficacy and safety of elenbecestat.