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Synonyms: dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]] | MIW815 | ML RR-S2 CDA  | S100
Compound class: Synthetic organic
Comment: ADU-S100 (a.k.a. ML RR-S2 CDA) is a synthetic cyclic dinucleotide STING agonist that is being developed as an immuno-oncology lead by Aduro BioTech and Novartis .
|Intratumoural STING activation by ADU-S100 induces CD8+ T cell-mediated anti-tumour immunity [1-2], indicating the translational potential of synthetic cyclic dinucleotide-derived STING agonists as cancer therapeutics.|