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Synonyms: compound 7 [PMID: 31751136]
Compound class: Synthetic organic
Comment: 4-OMe-ARM1 is an activator of leukotriene A4 hydrolase aminopeptidase activity .
|Modulation of LTA4 hydrolase aminopeptidase (AP; anti-inflammatory) and epoxide hydrolase (EH; pro-inflammatory) activities are being considered as a mechanism for targeting LTA4 hydrolase in inflammatory conditions. 4-OMe-ARM1 activates LTA4 hydrolase AP activity, which leads to a dose-dependent reduction of LTB4 production by human neutrophils .|