Ligand id: 9926

Name: bentamapimod

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 112.4
Molecular weight 457.16
XLogP 2.27
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Immune dysfunction is believed to be an underlying contributor to the pathogenesis of endometriosis. Bentamapimod interrupts immune pathways in preclinical endometriosis models [1,3], and reduces inflammatory cytokine levels in human endometriotic lesions [3].