Compound class:
Synthetic organic
Comment: CRAC channel inhibitor 5b is a selective ORAI1 inhibitor that was identified through SAR of CRAC channel inhibitor 1 [PMID: 26256403] [1].
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References |
1. Zhang HZ, Xu XL, Chen HY, Ali S, Wang D, Yu JW, Xu T, Nan FJ. (2015)
Discovery and structural optimization of 1-phenyl-3-(1-phenylethyl)urea derivatives as novel inhibitors of CRAC channel. Acta Pharmacol Sin, 36 (9): 1137-44. [PMID:26256403] |