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Synonyms: MK 571 | MK-0571 | MK571
Compound class: Synthetic organic
Comment: MK-571 is a stereo enantiomer of verlukast . Be aware of the confusion caused by incorrectly using MK-571 as a synonym for verlukast that has arisen in online resources.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Jones TR, Zamboni R, Belley M, Champion E, Charette L, Ford-Hutchinson AW, Gauthier JY, Leger S, Lord A, Masson P et al.. (1991)
Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571.
Can J Physiol Pharmacol, 69 (12): 1847-54. [PMID:1666333]
2. Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z et al.. (1999)
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Nature, 399 (6738): 789-93. [PMID:10391245]