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Synonyms: GW 9508 | GW-9508
Compound class: Synthetic organic
Comment: GW9508 is a free fatty acid receptor (FFA1R, GPR40) partial agonist with a range of in vivo effects.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C et al.. (2006)
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Br J Pharmacol, 148 (5): 619-28. [PMID:16702987]
2. Hirasawa A, Hara T, Katsuma S, Adachi T, Tsujimoto G. (2008)
Free fatty acid receptors and drug discovery.
Biol Pharm Bull, 31 (10): 1847-51. [PMID:18827341]