Synonyms: ADX-102 | ADX102 | example 5 [WO2018039197A1] | NS-2 | NS2 [1]
Compound class:
Synthetic organic
Comment: Reproxalap is a novel small molecule that acts as a molecular trap for pro-inflammatory Reactive Aldehyde Species (RASP) that was developed by Aldeyra Therapeutics. Reproxalap (as example 5; NS2) and its uses are claimed in Aldeyra patent WO2018039197A1 [1].
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References |
1. Kinney WA, Machatha SG, Young S. (2018)
Aldehyde trapping compounds and methods of use thereof. Patent number: WO2018039197A1. Assignee: Aldeyra Therapeutics, Inc.. Priority date: 22/08/2016. Publication date: 01/03/2018. |
2. Macdonald S, Cullen V, Brady T, Levi I, Meilin S, Young S. (2018)
ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain. J Pain Relief, Posters & Accepted Abstracts. DOI: 10.4172/2167-0846.C1.012 |