Synonyms: compound 15b [PMID: 28041831] | KAR-5585 | KAR5585 | RVT-1201
Compound class:
Synthetic organic
Comment: Rodatristat ethyl (KAR5585) is the inactive prodrug of rodatristat [1]. It is bioconverted in vivo by esterase activity.
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References |
1. Goldberg DR, De Lombaert S, Aiello R, Bourassa P, Barucci N, Zhang Q, Paralkar V, Stein AJ, Holt M, Valentine J et al.. (2017)
Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg Med Chem Lett, 27 (3): 413-419. [PMID:28041831] |