Synonyms: BC-3781 | BC3781 | compound 7 [PMID: 24874438] | Xenleta®
lefamulin is an approved drug (FDA (2019), EMA (2020))
Compound class:
Synthetic organic
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References |
1. Ling C, Fu L, Gao S, Chu W, Wang H, Huang Y, Chen X, Yang Y. (2014)
Design, synthesis, and structure-activity relationship studies of novel thioether pleuromutilin derivatives as potent antibacterial agents. J Med Chem, 57 (11): 4772-95. [PMID:24874438] |
2. Prince WT, Ivezic-Schoenfeld Z, Lell C, Tack KJ, Novak R, Obermayr F, Talbot GH. (2013)
Phase II clinical study of BC-3781, a pleuromutilin antibiotic, in treatment of patients with acute bacterial skin and skin structure infections. Antimicrob Agents Chemother, 57 (5): 2087-94. [PMID:23422913] |
3. Veve MP, Wagner JL. (2018)
Lefamulin: Review of a Promising Novel Pleuromutilin Antibiotic. Pharmacotherapy, 38 (9): 935-946. [PMID:30019769] |