Synonyms: DR-3355 | Levaquin® | Quinsair®
levofloxacin is an approved drug (FDA (1996), EMA (2015))
Compound class:
Synthetic organic
Comment: Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibacterial.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Bulik CC, Christensen H, Nicolau DP. (2010)
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance. Antimicrob Agents Chemother, 54 (1): 557-9. [PMID:19917762] |
2. Gellert M, Mizuuchi K, O'Dea MH, Nash HA. (1976)
DNA gyrase: an enzyme that introduces superhelical turns into DNA. Proc Natl Acad Sci U S A, 73 (11): 3872-6. [PMID:186775] |
3. Haas W, Pillar CM, Zurenko GE, Lee JC, Brunner LS, Morris TW. (2009)
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. Antimicrob Agents Chemother, 53 (8): 3552-60. [PMID:19506065] |
4. Morrow BJ, He W, Amsler KM, Foleno BD, Macielag MJ, Lynch AS, Bush K. (2010)
In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. Antimicrob Agents Chemother, 54 (5): 1955-64. [PMID:20176911] |