Synonyms: Avelox® | BAY-12-8039 | BAY-128039 | BAY128039 | MFX | MOXIVIG® (opthalmic solution)
moxifloxacin is an approved drug (FDA (1999), UK (2009))
Compound class:
Synthetic organic
Comment: Moxifloxacin is a fourth generation fluoroquinolone antibacterial. Compared to earlier generation fluoroquinolones it has expanded activity against Gram-positive bacteria and some atypical pathogens.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Gellert M, Mizuuchi K, O'Dea MH, Nash HA. (1976)
DNA gyrase: an enzyme that introduces superhelical turns into DNA. Proc Natl Acad Sci U S A, 73 (11): 3872-6. [PMID:186775] |
2. Lauderdale TL, Shiau YR, Lai JF, Chen HC, King CH. (2010)
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates. Antimicrob Agents Chemother, 54 (3): 1338-42. [PMID:20065058] |