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Synonyms: GAR-936 | GAR936 | Tygacil® | WAY-GAR-936
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bhavnani SM, Rubino CM, Ambrose PG, Babinchak TJ, Korth-Bradley JM, Drusano GL. (2010)
Impact of different factors on the probability of clinical response in tigecycline-treated patients with intra-abdominal infections.
Antimicrob Agents Chemother, 54 (3): 1207-12. [PMID:20038623]
2. Cercenado E, Marín M, Sánchez-Martínez M, Cuevas O, Martínez-Alarcón J, Bouza E. (2007)
In vitro activities of tigecycline and eight other antimicrobials against different Nocardia species identified by molecular methods.
Antimicrob Agents Chemother, 51 (3): 1102-4. [PMID:17194827]
3. Hajdu S, Holinka J, Reichmann S, Hirschl AM, Graninger W, Presterl E. (2010)
Increased temperature enhances the antimicrobial effects of daptomycin, vancomycin, tigecycline, fosfomycin, and cefamandole on staphylococcal biofilms.
Antimicrob Agents Chemother, 54 (10): 4078-84. [PMID:20679509]