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Synonyms: Ilube® (eye drops) | N-A-C Sustain® | N-Acetyl-cysteine | N-Acetyl-L-cysteine | NAC | Parvolex®
acetylcysteine is an approved drug (FDA (1963), UK (1992))
Compound class: Synthetic organic
Comment: Acetylcysteine is a prodrug for L-cysteine synthesis, and L-cysteine is a precursor to the biologic antioxidant glutathione. Hence adminstration of acetylcysteine replenishes glutathione stores.
1. Berk M, Malhi GS, Gray LJ, Dean OM. (2013)
The promise of N-acetylcysteine in neuropsychiatry.
Trends Pharmacol Sci, 34 (3): 167-77. [PMID:23369637]
2. Tam J, Nash EF, Ratjen F, Tullis E, Stephenson A. (2013)
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
Cochrane Database Syst Rev, (7): CD007168. [PMID:23852992]