Synonyms: L-Val-L-Val-3-amino-2-oxo-valeryl-D-Leu-L-Val
Compound class:
Natural product
Comment: Poststatin is produced by Streptomyces viridochromogenes MH534-30F3 [1]. It acts as an inhibitor of prolyl endopeptidase.
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References |
1. Nagai M, Ogawa K, Muraoka Y, Naganawa H, Aoyagi T, Takeuchi T. (1991)
Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. II. Structure determination and inhibitory activities. J Antibiot, 44 (9): 956-61. [PMID:1938618] |
2. Tsuda M, Muraoka Y, Nagai M, Aoyagi T, Takeuchi T. (1996)
Poststatin, a new inhibitor of prolyl endopeptidase. V. Endopeptidase inhibitory activity of poststatin analogues. J Antibiot, 49 (9): 890-9. [PMID:8931723] |